Brighton defender Tariq Lamptey and Athletic Bilbao forward Inaki Williams are among five players who have switched their international allegiance to Ghana.
London-born Lamptey, 21 represented England at youth levels while Williams, who was born in Bilbao to Ghanaian parents, was capped once by Spain,
Wing-back Lamptey had looked set to switch to the West Africans after asking to be left out of the England Under-21 squad for European U21 Championship qualifiers last month.
The pair join three players based in Germany - Stephen Ambrosius, Ransford-Yeboah Konigsdorffer and Patric Pfeiffer - in committing to the Black Stars ahead of the 2022 World Cup in Qatar.
Uncapped German-born defender Pfeiffer, 22, plays for Darmstadt 98, but Hamburg duo of Ambrosius, 23, and forward Konigsdorffer, 21, have both represented Germany at under-21 level.
The Ghana Football Association (GFA) expects their availability will help take the West Africans to the next level.
"The availability of these players means a lot to the Ghana Football Association and the technical team of the Black Stars," GFA president Kurt Okra said.
"We have always maintained that we will not limit ourselves to only a small group of players but would scout top talents across the globe who are ready to sacrifice for the nation and to take us to the next level.
"This gives the technical team more options to choose from adding to our continuous desire to improve the team.
"Coach Otto Addo and his technical team will continue to monitor and assess them for future assignments including the September games and the World Cup in Qatar."
Negative to positive headlines
The decision by the GFA to make public overtures toward diaspora-born players has often been characterised by negative headlines and caused polarisation among fans of the four-time African champions.
But slowly that is starting to change, following the recent capture and contribution of Belgian-born Denis Odoi towards their 2022 World Cup qualification.
"This [commitment of the quintet] follows exhaustive engagements between the leadership of the GFA, the players and their parents in the last few months. The players are therefore available for selection in our upcoming international fixtures," the GFA said in a statement.
Ghana are benefiting from a recent Fifa rule allowing players greater scope to switch national teams.
Players can switch national sides as long as they they have played no more than three competitive matches at senior level prior to them turning 21.
However, appearances in World Cup or continental finals such as the European Championships would prohibit a change of eligibility.
The new Black Stars
The availability of the quintet for Ghana comes as a huge boost ahead of this year's World Cup in Qatar, where the 2010 quarter-finalists will face Portugal, Uruguay and South Korea in Group H.
Williams, whose younger brother Nico also plays for Athletic, grew up wanting to play for Spain and represented them at youth level.
But after making his senior international bow for La Roja in 2015 in a 3-1 friendly win over Bosnia, he found the door of the national team shut to him.
After seven years of waiting, he is now delighted to swap the colours of Spain for the Black Stars kit.
"Today a new challenge begins. From now on, I will defend Ghana's T-shirt with all my will whilst I give my best. I'm one of the Black Stars," Williams said in a video on social media.
Back in May, Lamptey requested to be omitted from the England's U21 squad for matches against the Czech Republic, Albania, Kosovo and Slovenia.
Eligible for Ghana through his parents, his father Ahmed played a huge role, while former Brighton manager Chris Hughton - a technical advisor for the Black Stars - also made a significant input in Lamptey's decision.
Born in Germany, Ghana coach Addo was a major influence in convincing Odoi, 34, and the trio of Ambrosius, Konigsdorffer and Pfeiffer to pledge allegiances to the West African nation.
Addo, who has worked at former club Dortmund since 2019, represented Ghana at the World Cup in 2006, making two appearances at the event as the Black Stars reached the round of 16.
He guided Ghana to qualification for the 2022 World Cup, beating fierce West African rivals Nigeria on the away goals rule after a 1-1 draw in Abuja.
He recently extended his contract with Ghana until the end of December 2022.